PURITASTM APS-P phases are bonded with amino-propyl silane using our ultra pure spherical silica gel as base material. Depending on the choice of the eluent, it can both be used under normal andreversed phase mode. Especially, it is useful for saccharide separation using acetonitrile - water. The phase is also recommended for the separation of basic compounds under normal phase conditions, which could not be separated using unmodified silica gel. Simple eluents such as hexane - ethyl acetate or chloroform / methanol are used for the separation without any polar solvent additives.